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Structure of 1268810-07-6
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1-((Trimethylsilyl)ethynyl)cyclopropane-1-carboxylic acid features a sterically constrained cyclopropane ring bearing a silylated alkyne and carboxylic acid group, enabling direct incorporation into conjugation workflows. The trimethylsilyl moiety enhances stability and facilitates orthogonal deprotection, while the electron-deficient alkyne supports efficient copper-catalyzed coupling reactions under mild conditions.
1-((Trimethylsilyl)ethynyl)cyclopropane-1-carboxylic acid serves as a versatile building block for the synthesis of cyclopropyl-containing alkynes, enabling efficient access to functionalized scaffolds via copper-catalyzed azide-alkyne cycloaddition (CuAAC). The trimethylsilyl group provides enhanced stability and facilitates subsequent desilylation under mild conditions. Its carboxylic acid functionality allows for direct derivatization or incorporation into peptide-like architectures, making it valuable in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
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Lot numbers can be found on the outside label of a product: