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Structure of 7498-54-6
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3-(tert-Butyl)benzoic acid offers a sterically hindered aryl carboxylic acid functionality, combining enhanced solubility with robust stability under standard conditions. The tert-butyl group imparts significant steric bulk, reducing unwanted side reactions while maintaining compatibility with common coupling and derivatization protocols in synthetic organic chemistry and medicinal chemistry applications.
3-(tert-Butyl)benzoic acid serves as a versatile building block in medicinal chemistry and materials science, offering enhanced lipophilicity and steric bulk via its tert-butyl substituent. The carboxylic acid group enables direct coupling reactions, amidation, esterification, and derivatization under standard conditions. Its bench-stable nature and compatibility with diverse functional groups facilitate efficient synthesis of complex architectures, including heterocyclic scaffolds and bioactive analogs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: