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Structure of 1000340-51-1
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7-Methyl-2H-indazole-3-carbaldehyde features a fused bicyclic indazole core with a methyl group at the 7-position and an aldehyde handle at the 3-position. This combination delivers a sterically accessible, electron-deficient carbonyl site ideal for nucleophilic addition and coupling reactions in medicinal chemistry. The bench-stable aldehyde integrates readily into diverse heterocyclic scaffolds under mild conditions.
7-Methyl-2H-indazole-3-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the aldehyde position for Suzuki-Miyaura coupling, reductive amination, or imine formation. The indazole core provides enhanced metabolic stability and favorable binding interactions in kinase inhibitors and CNS-targeted therapeutics. Bench-stable and readily purified by flash chromatography, it functions efficiently in standard synthetic workflows requiring orthogonally protected heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: