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Structure of 100047-52-7
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5-Methyl-1H-pyrrole-3-carboxylic acid features a methyl-substituted pyrrole core with a carboxylic acid group at the 3-position, delivering enhanced solubility and stability under standard conditions. This electron-rich scaffold integrates readily into bioactive molecule design, particularly in medicinal chemistry scaffolds requiring heteroaromatic linkage. The para-methyl substitution modulates reactivity and metabolic resistance, enabling efficient coupling reactions in peptide and macrocycle synthesis.
5-Methyl-1H-pyrrole-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrrole-based heterocycles. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions under standard conditions. The methyl group enhances metabolic stability and provides a handle for further functionalization. Bench-stable and readily purified by recrystallization, it functions reliably in peptide mimetics, kinase inhibitors, and other API scaffolds requiring substituted pyrroles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: