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Structure of 1000802-75-4
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This boronic acid features a methoxy-substituted pyridine core with methyl and boronic acid functionalities positioned for efficient cross-coupling. The electron-donating methoxy group enhances reactivity, while the ortho-methyl substituent provides steric control. Bench-stable under standard conditions, it integrates seamlessly into Suzuki-Miyaura coupling workflows for constructing complex heterocyclic architectures.
(2-Methoxy-6-methylpyridin-3-yl)boronic acid serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl architectures. Its moderate steric profile and functional group tolerance facilitate reliable coupling with aryl halides and triflates under standard conditions. The methoxy and methyl substituents enhance solubility and stability, supporting straightforward handling and purification—ideal for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: