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Structure of 1001020-17-2
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This pyrazole aldehyde features a sterically hindered tert-butyl group that enhances stability and solubility in organic media. The aldehyde moiety enables direct coupling in Ugi, Mannich, or reductive amination reactions. Its electron-deficient heterocyclic core supports efficient functionalization under mild conditions.
3-(tert-Butyl)-1H-pyrazole-4-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyrazole-based scaffolds via standard condensation and coupling reactions. The aldehyde group facilitates efficient derivatization, including reductive amination and Grignard additions, while the tert-butyl substituent enhances steric stability and solubility. Its bench-stable nature and compatibility with diverse functional groups make it well-suited for high-throughput synthesis and API intermediate development.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: