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Structure of 1002359-91-2
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tert-Butyl (3R)-3-(bromomethyl)piperidine-1-carboxylate delivers a chiral, bench-stable bromomethyl handle at the 3-position of a piperidine ring. This configurationally stable derivative integrates readily into asymmetric synthesis workflows, enabling selective functionalization via nucleophilic substitution. Its steric protection from the tert-butyl group enhances stability during handling and purification.
tert-Butyl (3R)-3-(bromomethyl)piperidine-1-carboxylate serves as a versatile chiral building block for the synthesis of bioactive piperidine derivatives. The bromomethyl group enables efficient nucleophilic substitution reactions, facilitating the installation of diverse side chains under mild conditions. Its tert-butyl carbamate protection offers excellent bench stability and compatibility with a broad range of functional groups, simplifying purification and enabling straightforward deprotection in late-stage synthesis.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H314
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Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501
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Lot numbers can be found on the outside label of a product: