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Structure of 1002535-21-8
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3-(1H-Pyrazol-4-yl)benzoic acid features a conjugated aryl-boronic acid scaffold with a pyrazole-containing heterocycle, enabling efficient cross-coupling reactions. The carboxylic acid group provides a handle for derivatization, while the electron-rich pyrazole ring enhances reactivity in palladium-catalyzed transformations. This compound serves as a key intermediate in the synthesis of bioactive molecules and functional materials.
3-(1H-Pyrazol-4-yl)benzoic acid serves as a versatile building block for constructing bioactive heterocyclic scaffolds, enabling efficient coupling in amide bond formation and Suzuki-Miyaura cross-coupling reactions. The carboxylic acid group provides ready access to esters, amides, and acyl chlorides, while the pyrazole moiety offers robust hydrogen-bonding capacity and metabolic stability. Its bench-stable, crystalline nature facilitates straightforward isolation and purification, making it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330
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Lot numbers can be found on the outside label of a product: