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Structure of 1003-21-0
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5-Bromo-1-methyl-1H-imidazole features a bromine substituent at the 5-position and a methyl group at nitrogen-1, delivering a sterically hindered, electron-deficient imidazole core. This configuration enhances stability under standard conditions while enabling selective coupling reactions in synthetic applications.
5-Bromo-1-methyl-1H-imidazole serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, while the N-methylated imidazole core provides enhanced stability and solubility. The molecule functions effectively in Suzuki-Miyaura and Negishi couplings, facilitating the construction of biologically active scaffolds. Bench-stable and easily purified by recrystallization, it supports scalable synthesis workflows for drug discovery and functional materials development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: 3335
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: