2-Bromo-5-hydroxy-3-methylpyridine

Name: 2-Bromo-5-hydroxy-3-methylpyridine
Brand: ChemScene
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CAS No. 1003711-43-0
Cat. No. CS-W018711
Purity≥98%
MDL No.MFCD09839267

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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2-Bromo-5-hydroxy-3-methylpyridine|CS-W018711

Structure of 1003711-43-0

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Description

2-Bromo-5-hydroxy-3-methylpyridine features a regioselective substitution pattern enabling direct functionalization in late-stage synthesis. The hydroxy group supports hydrogen bonding and solubility enhancements, while the bromine serves as a high-reactivity handle for cross-coupling. This pyridine scaffold combines bench-stable handling with compatibility across diverse reaction conditions.

Application

2-Bromo-5-hydroxy-3-methylpyridine serves as a versatile building block for the synthesis of functionalized pyridine derivatives. The bromo group enables palladium-catalyzed cross-coupling reactions, while the hydroxyl and methyl functionalities offer sites for selective derivatization. Its bench-stable nature and compatibility with standard protection/deprotection sequences facilitate efficient access to complex heterocyclic scaffolds in medicinal chemistry and agrochemical research.

General Information

CAS No. 1003711-43-0
Cat. No. CS-W018711
Purity ≥98%
MDL No. MFCD09839267
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₆BrNO
Molecular Weight 188.02
Synonym(s) 6-Bromo-5-methylpyridin-3-ol
SMILES CC1=CC(O)=CN=C1Br

Computational Chemistry Data

TPSA 33.12
LogP 1.85812
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2-Bromo-5-hydroxy-3-methylpyridine

CAS No. 1003711-43-0

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