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Structure of 10057-46-2
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6-(Trifluoromethyl)-1H-benzo[d]imidazol-2-amine features a trifluoromethyl group at the 6-position, enhancing electron-withdrawal and metabolic stability. This bench-stable heterocycle integrates readily into pharmaceutical scaffolds, offering improved solubility and bioavailability in target-directed drug discovery.
6-(Trifluoromethyl)-1H-benzo[d]imidazol-2-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard coupling and functionalization reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the imidazole nitrogen supports hydrogen bonding and coordination in target interactions. The compound exhibits bench stability and compatibility with common synthetic protocols, facilitating purification and integration into multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: