(R)-4-Methyl-1,3,2-dioxathiolane 2,2-dioxide

Name: (R)-4-Methyl-1,3,2-dioxathiolane 2,2-dioxide
Brand: ChemScene
Availability: InStock
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CAS No. 1006381-03-8
Cat. No. CS-0084570
Purity≥98%
MDL No.MFCD26131319

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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(R)-4-Methyl-1,3,2-dioxathiolane 2,2-dioxide|CS-0084570

Structure of 1006381-03-8

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Description

(R)-4-Methyl-1,3,2-dioxathiolane 2,2-dioxide is a chiral sulfone-containing heterocycle featuring a stereogenic center at the C4 position. This bench-stable, moisture-tolerant scaffold integrates readily into asymmetric synthesis workflows, serving as a key building block for sulfur-based pharmaceutical intermediates and functionalized organic molecules.

Application

(R)-4-Methyl-1,3,2-dioxathiolane 2,2-dioxide serves as a stable, bench-ready chiral synthon for the construction of sulfonate-containing heterocycles. Its well-defined stereochemistry enables stereoselective transformations in asymmetric synthesis, particularly in the development of nucleoside analogs and sulfonamide-based pharmaceutical intermediates. The molecule exhibits excellent functional group tolerance and facilitates efficient coupling reactions under mild conditions, making it a practical choice for complex molecule assembly in medicinal chemistry workflows.

General Information

CAS No. 1006381-03-8
Cat. No. CS-0084570
Purity ≥98%
MDL No. MFCD26131319
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃H₆O₄S
Molecular Weight None
Synonym(s) 1,3,2-Dioxathiolane, 4-methyl-, 2,2-dioxide, (4R)-
SMILES O=S1(OC[C@@H](C)O1)=O

Computational Chemistry Data

TPSA 52.6
LogP -0.3335
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06
Signal Word : Danger	UN#: 2810
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H302-H340
Precautionary Statements : P264-P270-P330-P405-P501

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Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Drug Discovery Metabolic Disease GLP-1R

Key Words

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(R)-4-Methyl-1,3,2-dioxathiolane 2,2-dioxide

CAS No. 1006381-03-8

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