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Structure of 1006876-27-2
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N,N-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinamide features a boronate ester group paired with a pyridine amide motif, enabling efficient cross-coupling under mild conditions. This bench-stable reagent integrates seamlessly into Suzuki-Miyaura reactions, offering predictable regiochemistry and compatibility with diverse functional groups.
N,N-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinamide serves as a versatile boron-containing building block for palladium-catalyzed cross-coupling reactions. The picolinamide moiety provides a robust nitrogen-directed coupling site, while the pinacol boronate ester ensures excellent stability and compatibility with diverse reaction conditions. This reagent facilitates efficient C–C bond formation in late-stage functionalization and heterocyclic scaffold elaboration, offering reliable yields and straightforward purification.
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GHS Pictogram :
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GHS No : GHS06,GHS08,GHS09
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H315-H317-H319-H330-H334-H335-H370-H410
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Precautionary Statements : P260-P261-P264-P270-P271-P272-P273-P280-P284-P302+P352-P304+P340-P362+P364-P391-P405-P501
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Lot numbers can be found on the outside label of a product: