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CS-W001157 4
Total: USD 88.00

2,5-Dibromophenylboronicacid

  • CAS No. 1008106-93-1

  • Cat. No. CS-W020403
  • Purity≥97%
  • MDL No.MFCD09743927

*For research and further manufacturing use only, not for direct human use.

2,5-Dibromophenylboronicacid|CS-W020403

Structure of 1008106-93-1

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General Information

  • CAS No. 1008106-93-1
  • Cat. No. CS-W020403
  • Purity ≥97%
  • MDL No. MFCD09743927
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BBr₂O₂
  • Molecular Weight 279.72
  • Synonym(s) 2,5-Dibromophenylboronic acid
  • SMILES OB(O)C1=CC(Br)=CC=C1Br

Description

2,5-Dibromophenylboronic acid features two bromine substituents at the 2- and 5-positions of the phenyl ring, enhancing its reactivity in cross-coupling transformations. The boronic acid moiety enables direct incorporation into Suzuki-Miyaura reactions under mild conditions. This configuration delivers high functional group tolerance and stability during storage and handling.

Application

2,5-Dibromophenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds with high functional group tolerance. The ortho-bromine substituents provide additional sites for sequential coupling or derivatization, enhancing molecular complexity in medicinal chemistry and materials synthesis. Its bench-stable solid form facilitates handling and purification, making it well-suited for scalable, multi-step syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   0.8914
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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