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Structure of 100859-84-5
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2-Chloroisonicotinamide delivers a moisture-tolerant, bench-stable platform for constructing bioactive heterocycles. The para-chloro group enables direct functionalization in cross-coupling reactions, while the amide functionality provides directional hydrogen bonding and enhanced solubility in polar solvents.
2-Chloroisonicotinamide serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds via nucleophilic substitution and coupling reactions. Its ortho-chloro functionality provides high reactivity for palladium-catalyzed cross-couplings, while the pyridine amide group offers excellent solubility and compatibility with diverse reaction conditions. The compound exhibits robust bench stability and facilitates straightforward purification, making it ideal for iterative synthesis campaigns and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: