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Structure of 100991-19-3
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2-(Difluoromethyl)pyrimidin-5-ol features a difluoromethyl group attached to a pyrimidin-5-ol scaffold, delivering enhanced metabolic stability and favorable electronic properties. This configuration enables robust integration into bioactive molecules, particularly in medicinal chemistry applications requiring halogenated heterocycles with improved lipophilicity and target affinity.
2-(Difluoromethyl)pyrimidin-5-ol serves as a versatile building block in medicinal chemistry, enabling the introduction of a polar, metabolically stable difluoromethyl group adjacent to a hydrogen-bond-capable hydroxypyrimidine scaffold. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient incorporation into bioactive heterocycles, particularly in kinase inhibitor and antiviral agent development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319
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Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: