Lot numbers can be found on the outside label of a product:
2-Chloro-3-pyridineacetonitrile
-
CAS No. 101012-32-2
- Cat. No. CS-W020736
- Purity≥98%
- MDL No.MFCD09923767
*For research and further manufacturing use only, not for direct human use.
Structure of 101012-32-2
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 101012-32-2
- Cat. No. CS-W020736
- Purity ≥98%
- MDL No. MFCD09923767
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₇H₅ClN₂
- Molecular Weight 152.58
- Synonym(s) (2-Chloropyridin-3-yl)acetonitrile; 2-Chloro-3-cyanomethylpyridine; 2-Chloropyridine-3-acetonitrile
- SMILES N#CCC1=CC=CN=C1Cl
Description
2-Chloro-3-pyridineacetonitrile features a chlorinated pyridine core paired with a nitrile-bearing acetyl side chain, enabling direct incorporation into heterocyclic scaffolds. This bench-stable reagent facilitates efficient synthesis of bioactive pyridine derivatives through nucleophilic substitution and transition-metal-catalyzed coupling reactions.
Application
2-Chloro-3-pyridineacetonitrile serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyridine-based scaffolds. Its dual functionality—reactive chloro group and electron-deficient nitrile—facilitates nucleophilic substitution, palladium-catalyzed coupling, and heterocycle elaboration under standard conditions. The compound exhibits good bench stability and compatibility with common protecting groups, facilitating purification and integration into multi-step syntheses.
Synthesis
-
Route1
-
6635-88-7 - ~43%
-
In-stock
101012-32-2
References
-
Aventis Pharmaceuticals Inc. Patent: US2005/54631 A1, 2005 ; Location in patent: Page/Page column 23-24 ;
-
-
Route2
-
In-stock
89581-84-0 -
143-33-9
- ~61%
-
In-stock
101012-32-2
References
-
Takeda Pharmaceutical Company Limited Patent: EP2018863 A1, 2009 ; Location in patent: Page/Page column 74 ;
-
-
Route3
-
In-stock
89581-84-0
-
151-50-8
- ~80%
-
In-stock
101012-32-2
References
-
UCB PHARMA S.A. Patent: WO2009/13462 A1, 2009 ; Location in patent: Page/Page column 25-26 ; WO 2009/013462 A1
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 36.68
- LogP 1.80108
- H_Acceptors 2
- H_Donors 0
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 2-Chloro-3-pyridineacetonitrile sigma2-Chloro-3-pyridineacetonitrile manufacturer2-Chloro-3-pyridineacetonitrile price2-Chloro-3-pyridineacetonitrile structure2-Chloro-3-pyridineacetonitrile SDSbuy 2-Chloro-3-pyridineacetonitrile2-Chloro-3-pyridineacetonitrile supplier2-Chloro-3-pyridineacetonitrile uses2-Chloro-3-pyridineacetonitrile molecular weightprice of 2-Chloro-3-pyridineacetonitrile2-Chloro-3-pyridineacetonitrile chemical name formula of 2-Chloro-3-pyridineacetonitrile