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Structure of 10128-72-0
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Methyl 3-hydroxyisonicotinate features a pyridine ring bearing both methyl ester and hydroxyl substituents at the meta and para positions, respectively. This arrangement imparts enhanced solubility in polar organic solvents and facilitates downstream derivatization in synthetic routes. The compound exhibits stability under standard bench conditions and serves as a key intermediate in the construction of bioactive heterocycles and pharmaceutical precursors.
Methyl 3-hydroxyisonicotinate serves as a versatile building block in synthetic organic chemistry, enabling the construction of pyridine-based heterocycles and bioactive scaffolds. The ortho-hydroxyl group facilitates directed metalation and subsequent functionalization, while the ester moiety supports selective transformations under mild conditions. Its bench-stable nature and compatibility with common coupling and reduction protocols make it a practical choice for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: