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Structure of 10128-73-1
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3-Hydroxyisonicotinamide features a hydroxyl group at the 3-position of an isonicotinamide scaffold, enabling direct hydrogen bonding and enhanced solubility in polar solvents. This configuration supports its role as a versatile scaffold in medicinal chemistry, where it integrates into bioactive molecules through modular derivatization. The compound exhibits bench-stable handling under standard conditions.
3-Hydroxyisonicotinamide serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyridine-based heterocycles and bioactive scaffolds. Its ortho-hydroxypyridine motif facilitates metal coordination and hydrogen bonding, while the amide functionality offers stability and polarity for downstream derivatization. The compound exhibits good bench stability and is compatible with standard coupling and functionalization protocols, making it a practical choice for library synthesis and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: