Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Methoxybenzenesulfonyl chloride

  • CAS No. 10130-87-7

  • Cat. No. CS-W007645
  • Molecule weight206.65
  • Purity≥96%
  • MDL No.MFCD01961367

*For research and further manufacturing use only, not for direct human use.

2-Methoxybenzenesulfonyl chloride|CS-W007645

Structure of 10130-87-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 10130-87-7
  • Cat. No. CS-W007645
  • Purity ≥96%
  • MDL No. MFCD01961367
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇ClO₃S
  • Molecular Weight 206.65
  • Synonym(s) 5-Methoxybenzenesulfonyl chloride
  • SMILES O=S(C1=CC=CC=C1OC)(Cl)=O

Description

2-Methoxybenzenesulfonyl chloride features a methoxy-substituted benzene ring linked to a sulfonyl chloride group, enabling direct incorporation into sulfonamide and sulfonate derivatives. This reagent offers enhanced solubility in organic solvents and improved stability under standard bench conditions, facilitating efficient functionalization in synthetic workflows involving aromatic sulfonylation.

Application

2-Methoxybenzenesulfonyl chloride serves as a versatile sulfonylating agent for the efficient introduction of sulfonamide functionalities. It exhibits good bench stability and reacts selectively with primary and secondary amines under mild conditions, enabling straightforward synthesis of sulfonamide derivatives. The methoxy group enhances solubility in organic solvents and provides a handle for further functionalization. This reagent is particularly useful in medicinal chemistry for constructing sulfonamide-based pharmacophores and in process chemistry due to its compatibility with diverse functional groups and ease of purification.

Synthesis

  • Route1
    • null|null
      100-66-3
    • ~82%
    • In-stock
      2-Methoxybenzenesulfonyl chloride|CS-W007645
      10130-87-7

    References

    • Milburn, Robert R.; Snieckus, Victor Angewandte Chemie - International Edition, 2004 , vol. 43, # 7 p. 892 - 894
  • Route2

    References

    • Debergh, J. Robb; Niljianskul, Nootaree; Buchwald, Stephen L. Journal of the American Chemical Society, 2013 , vol. 135, # 29 p. 10638 - 10641
  • Route3
    • null|null
      90-04-0
    • ~22%
    • In-stock
      2-Methoxybenzenesulfonyl chloride|CS-W007645
      10130-87-7

    References

    • Binisti, Carine; Assogba, Leon; Touboul, Estera; Mounier, Carine; Huet, Jack; Ombetta, Jean-Edouard; Dong, Chang Zhi; Redeuilh, Catherine; Heymans, Francoise; Godfroid, Jean-Jacques European Journal of Medicinal Chemistry, 2001 , vol. 36, # 10 p. 809 - 828

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   43.37
  • LogP   1.6227
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Methoxybenzenesulfonyl chloride sigma2-Methoxybenzenesulfonyl chloride manufacturer2-Methoxybenzenesulfonyl chloride price2-Methoxybenzenesulfonyl chloride structure2-Methoxybenzenesulfonyl chloride SDSbuy 2-Methoxybenzenesulfonyl chloride2-Methoxybenzenesulfonyl chloride supplier2-Methoxybenzenesulfonyl chloride uses2-Methoxybenzenesulfonyl chloride molecular weightprice of 2-Methoxybenzenesulfonyl chloride2-Methoxybenzenesulfonyl chloride chemical name formula of 2-Methoxybenzenesulfonyl chloride
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label