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Structure of 10130-89-9
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4-(Chlorosulfonyl)benzoic acid was used in the preparation of polymer bound transfer hydrogenation catalyst and 4-(carboxymethyl-sulfamoyl)-benzoyladenosine. It was also used as a reagent in the sulfonation of -cyclodextrin.
4-(Chlorosulfonyl)benzoic acid serves as a versatile bifunctional building block, enabling direct installation of sulfonate and carboxylic acid groups in close proximity. Its chlorosulfonyl group reacts readily with amines and alcohols to form sulfonamide and sulfonic ester derivatives, while the carboxylic acid facilitates amide coupling or salt formation. The molecule exhibits good bench stability and is widely used in the synthesis of sulfonamide-containing pharmaceuticals and functionalized heterocycles.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314-H318
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: