6(5H)-Phenanthridinone

Name: 6(5H)-Phenanthridinone
Brand: ChemScene
Availability: InStock
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CAS No. 1015-89-0
Cat. No. CS-0019648
Purity≥98%
MDL No.MFCD00004988

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Description

6-(5H)-Phenanthridinone is an inhibitor of poly(ADP-ribose)polymerase (PARP)-1 activity. The ability of 6-(5H)-phenanthridinone to potentiate the effect of ionizing radiation on tumour cells was evaluated. Action of 6-(5H)-phenanthridinone, one of the most potent PARP inhibitor, on RDM4 murine lymphoma cells in culture was evaluated.Reactant involved in:Synthesis of 5,6-dihydrophenanthridine sulfonamidesOxidative coupling with diphenylacetyleneDirect copper acetate-catalyzed N-cyclopropylation of cyclic amidesReactant involved in the synthesis and/or pharmacological activity of biologically active molecules including:Potassium channel KV1.3 and IK-1 inhibitorsHIV-1 integrase inhibitors

General Information

CAS No. 1015-89-0
Cat. No. CS-0019648
Purity ≥98%
MDL No. MFCD00004988
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₉NO
Molecular Weight None
Synonym(s) None
SMILES O=C1NC2=CC=CC=C2C3=C1C=CC=C3

Computational Chemistry Data

TPSA 32.86
LogP 2.6813
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 0

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Other aromatic heterocycles compounds

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6(5H)-Phenanthridinone

CAS No. 1015-89-0

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