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CS-W001157 4
Total: USD 88.00

(E)-4-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)pyridine

  • CAS No. 1015243-13-6

  • Cat. No. CS-0867647
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(E)-4-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)pyridine|CS-0867647

Structure of 1015243-13-6

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General Information

  • CAS No. 1015243-13-6
  • Cat. No. CS-0867647
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₈BNO₂
  • Molecular Weight 231.10
  • Synonym(s) None
  • SMILES CC1(C)C(C)(C)OB(/C=C/C2=CC=NC=C2)O1

Description

This (E)-configured vinylpyridine boronate integrates readily into Suzuki-Miyaura coupling reactions, delivering functionalized pyridyl motifs with high regiocontrol. The tetramethylborolane moiety ensures stability and compatibility under standard conditions, enabling efficient cross-coupling with aryl and heteroaryl halides.

Application

(E)-4-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)pyridine serves as a versatile Suzuki-Miyaura coupling partner, enabling efficient construction of biaryl and styryl architectures. The boronate ester functionality offers excellent bench stability and compatibility with diverse reaction conditions. Its (E)-configured vinyl linkage ensures defined stereochemistry in final products, while the pyridine moiety provides a valuable heterocyclic scaffold for medicinal chemistry applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   31.35
  • LogP   2.7262
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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