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Structure of 1018678-49-3
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2-(Difluoromethyl)benzyl alcohol features a difluoromethyl group directly attached to a benzyl scaffold, delivering enhanced metabolic stability and lipophilicity. This structural motif integrates readily into bioactive molecules, serving as a valuable building block in medicinal chemistry for modulating pharmacokinetic properties.
2-(Difluoromethyl)benzyl alcohol serves as a versatile building block for fluorinated aromatic systems, enabling efficient access to bioactive scaffolds through standard functional group interconversions. Its bench-stable nature and tolerance to common reaction conditions facilitate downstream transformations such as oxidation to the carboxylic acid, reduction to the aldehyde, or incorporation into heterocycles via coupling reactions. The difluoromethyl group imparts enhanced metabolic stability and modulates electronic properties, making it valuable in medicinal chemistry and agrochemical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: