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Structure of 1023812-90-9
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2-(tert-Butyl)isonicotinaldehyde features a sterically hindered tert-butyl group flanking a pyridine ring, enhancing stability and solubility in organic media. This electron-deficient aldehyde integrates readily into cross-coupling reactions and serves as a key building block for bioactive heterocycles and functional materials under standard conditions.
2-(tert-Butyl)isonicotinaldehyde serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling efficient access to functionalized pyridine derivatives. Its aldehyde functionality facilitates nucleophilic additions, reductive aminations, and condensation reactions under mild conditions. The sterically hindered tert-butyl group enhances bench stability and minimizes undesired side reactions, while the isonicotinamide core supports diverse transformations including Suzuki-Miyaura coupling and heterocycle formation. This compound functions effectively in multistep syntheses requiring robust, orthogonal reactivity and clean purification profiles.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: