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Structure of 1023817-10-8
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Ethyl 2-(6-chloropyridazin-3-yl)acetate features a chlorinated pyridazine core linked to an ethyl ester-functionalized acetyl side chain. This compound serves as a key intermediate in the synthesis of bioactive heterocycles, particularly within medicinal chemistry programs targeting kinase inhibitors and antiviral agents. The electron-deficient pyridazine ring enhances reactivity in nucleophilic substitution processes, while the ester moiety enables further derivatization via hydrolysis or coupling reactions. Bench-stable under standard conditions, it facilitates efficient incorporation into complex molecular architectures without requiring stringent handling protocols.
Ethyl 2-(6-chloropyridazin-3-yl)acetate serves as a versatile building block for constructing pyridazinone-based heterocycles and bioactive scaffolds. The electrophilic chloro group enables facile nucleophilic substitution, while the ester functionality supports subsequent transformations such as hydrolysis, reduction, or coupling reactions. Its bench-stable nature and compatibility with standard synthetic protocols make it well-suited for medicinal chemistry campaigns and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P261-P280-P304+P340
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Lot numbers can be found on the outside label of a product: