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Structure of 1025509-77-6
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2-Methylpyridine-4-sulfonyl chloride features a pyridine ring with methyl and sulfonyl chloride groups in a 2,4-arrangement, delivering a reactive electrophilic site for nucleophilic substitution. This configuration enhances solubility in organic solvents while maintaining stability under anhydrous conditions, enabling efficient incorporation into pharmaceutical intermediates and functionalized materials.
2-Methylpyridine-4-sulfonyl chloride serves as a versatile sulfonylating agent in medicinal chemistry, enabling efficient introduction of the pyridylsulfonyl group into target molecules. Its reactivity facilitates amide and sulfonamide formation under mild conditions, with good bench stability and ease of purification. The methyl substituent enhances lipophilicity and can influence downstream metabolic properties, making it valuable for constructing bioactive scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: