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Structure of 1026796-39-3
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5-Hydroxymethylthiophene-2-boronic acid pinacol ester delivers a synthetically accessible boronate handle tethered to a thiophene scaffold, enabling efficient cross-coupling reactions. The pinacol ester enhances stability and solubility under standard conditions, while the hydroxymethyl group provides a site for further functionalization. This compound serves as a key intermediate in the synthesis of biologically active heterocycles and advanced materials.
5-Hydroxymethylthiophene-2-boronic acid pinacol ester serves as a stable, bench-ready building block for Suzuki-Miyaura coupling reactions. The pinacol boronate ester enhances shelf life and simplifies handling, while the hydroxymethyl group provides a versatile handle for further functionalization. It enables efficient access to substituted thiophene scaffolds common in pharmaceutical and agrochemical research, demonstrating good tolerance to diverse reaction conditions and facilitating rapid diversification in late-stage synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
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Lot numbers can be found on the outside label of a product: