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Structure of 10268-12-9
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Methyl 2-(3-nitrophenyl)acetate is a bench-stable, moisture-tolerant ester featuring a para-nitro-substituted aryl group. This electron-deficient aromatic system enables efficient coupling reactions and serves as a key intermediate in synthetic routes to bioactive heterocycles. The methyl ester functionality offers straightforward derivatization under standard conditions.
Methyl 2-(3-nitrophenyl)acetate serves as a versatile building block for nitroaryl-containing scaffolds, enabling efficient functionalization at the ortho-position relative to the phenyl ring. Its stability under standard reaction conditions and compatibility with diverse transformations—such as reduction of the nitro group, nucleophilic substitution, and transition-metal-catalyzed coupling—facilitates access to intermediates for pharmaceutical and agrochemical synthesis. The ester functionality allows straightforward manipulation via hydrolysis or derivatization, supporting modular route design.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: