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Structure of 102846-13-9
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3-(Bromomethyl)-1-methyl-1H-pyrazole serves as a reactive alkylating agent featuring a bromomethyl group attached to the pyrazole ring. This configuration enables efficient coupling in nucleophilic substitution reactions, particularly useful in synthesizing functionalized heterocycles. The molecule exhibits favorable reactivity under mild conditions and maintains stability during storage.
3-(Bromomethyl)-1-methyl-1H-pyrazole serves as a versatile electrophilic building block for C–C and C–heteroatom bond formation. Its bromomethyl group enables efficient alkylation, Suzuki-Miyaura coupling, and nucleophilic substitution reactions under mild conditions. The pyrazole scaffold provides metabolic stability and hydrogen-bonding capability, making it useful in medicinal chemistry lead optimization. Bench-stable and readily purified by distillation, it functions reliably in multi-step synthesis and API intermediate development.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H302-H314
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Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501
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Lot numbers can be found on the outside label of a product: