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CS-W001157 4
Total: USD 88.00

tert-Butyl D-serinate hydrochloride

  • CAS No. 1033753-14-8

  • Cat. No. CS-0158857
  • Molecule weight197.66
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl D-serinate hydrochloride|CS-0158857

Structure of 1033753-14-8

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General Information

  • CAS No. 1033753-14-8
  • Cat. No. CS-0158857
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₆ClNO₃
  • Molecular Weight 197.66
  • Synonym(s) D-Serine,1,1-dimethylethylester,hydrochloride
  • SMILES N[C@H](CO)C(OC(C)(C)C)=O.[H]Cl

Description

tert-Butyl D-serinate hydrochloride features a stable, moisture-tolerant tert-butyl ester protecting group coupled with a D-configured serine backbone. This configuration enables efficient incorporation into peptide sequences under standard coupling conditions, offering enhanced solubility and reduced epimerization risk during synthetic workflows.

Application

tert-Butyl D-serinate hydrochloride serves as a stable, bench-ready chiral building block for peptide synthesis and medicinal chemistry. Its tert-butyl ester group enables orthogonal protection under acidic conditions, while the D-serine backbone provides a stereodefined scaffold for constructing bioactive peptides and heterocyclic systems. The hydrochloride salt enhances solubility and handling, facilitating straightforward purification and integration into standard coupling protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   72.55
  • LogP   0.0695
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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