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CS-W001157 4
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Methyl 1H-pyrazolo[4,3-b]pyridine-5-carboxylate

  • CAS No. 1033772-23-4

  • Cat. No. CS-0054694
  • Molecule weight177.16
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 1H-pyrazolo[4,3-b]pyridine-5-carboxylate|CS-0054694

Structure of 1033772-23-4

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General Information

  • CAS No. 1033772-23-4
  • Cat. No. CS-0054694
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇N₃O₂
  • Molecular Weight 177.16
  • Synonym(s) Methyl 1H-pyrazolo[4
  • SMILES O=C(C1=CC=C(NN=C2)C2=N1)OC

Description

Methyl 1H-pyrazolo[4,3-b]pyridine-5-carboxylate is a heterocyclic ester featuring a fused pyrazole-pyridine core with a methyl carboxylate handle at the 5-position. This scaffold integrates electron-deficient aromaticity with synthetic versatility, enabling direct incorporation into medicinal chemistry libraries and transition-metal-catalyzed coupling reactions under standard conditions.

Application

Methyl 1H-pyrazolo[4,3-b]pyridine-5-carboxylate serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its pyrazolopyridine core enables straightforward functionalization at the 5-position via cross-coupling or nucleophilic substitution. The methyl ester group facilitates further derivatization, while the scaffold exhibits good bench stability and compatibility with standard synthetic protocols.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   67.87
  • LogP   0.7445
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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