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CS-W001157 4
Total: USD 88.00

2-(4-Ethynylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

  • CAS No. 1034287-04-1

  • Cat. No. CS-0127946
  • Purity≥97%
  • MDL No.MFCD16294504

*For research and further manufacturing use only, not for direct human use.

2-(4-Ethynylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0127946

Structure of 1034287-04-1

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General Information

  • CAS No. 1034287-04-1
  • Cat. No. CS-0127946
  • Purity ≥97%
  • MDL No. MFCD16294504
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₇BO₂
  • Molecular Weight 228.09
  • Synonym(s) 4-Ethynylbenzeneboronic Acid Pinacol Ester
  • SMILES C#CC1=CC=C(B2OC(C)(C)C(C)(C)O2)C=C1

Application

2-(4-Ethynylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-ready boron building block for palladium-catalyzed cross-coupling reactions. Its ethynyl group enables efficient Sonogashira coupling, while the tetramethyl-substituted dioxaborolane core ensures excellent shelf stability and compatibility with diverse functional groups. This reagent facilitates rapid assembly of conjugated biaryl and styryl architectures in medicinal chemistry and materials synthesis workflows.

Synthesis

  • Route1
    • In-stock
      4-Bromophenylacetylene|CS-W007542
      766-96-1
    • null|null
      61676-62-8
    • ~68%
    • In-stock
      2-(4-Ethynylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0127946
      1034287-04-1

    References

    • Journal of Polymer Science, Part A: Polymer Chemistry, , vol. 49, # 15 p. 3355 - 3365
  • Route2
    • null|null
      90965-06-3
    • In-stock
      4-Formylbenzeneboronic acid pinacol ester|CS-W000866
      128376-64-7
    • ~%
    • In-stock
      2-(4-Ethynylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0127946
      1034287-04-1

    References

    • Synlett, , # 19 p. 3037 - 3041
  • Route3

    References

    • Journal of Polymer Science, Part A: Polymer Chemistry, , vol. 49, # 15 p. 3355 - 3365

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   1.9671
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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