Lot numbers can be found on the outside label of a product:
4-Nitrophenyl β-D-glucuronide
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CAS No. 10344-94-2
- Cat. No. CS-0098151
- Purity≥98%
- MDL No.MFCD00036210
*For research and further manufacturing use only, not for direct human use.
Structure of 10344-94-2
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General Information
- CAS No. 10344-94-2
- Cat. No. CS-0098151
- Purity ≥98%
- MDL No. MFCD00036210
- Storage -20°C, protect from light, stored under nitrogen
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₂H₁₃NO₉
- Molecular Weight 315.23
- Synonym(s) pNPG_1
- SMILES OC([C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC2=CC=C(C=C2)[N+]([O-])=O)=O
Description
4-Nitrophenyl β-D-glucuronide serves as a sensitive chromogenic substrate for glucuronidase enzymes. The β-D-glucuronide linkage enables selective hydrolysis, releasing 4-nitrophenol under enzymatic action. This reaction produces a distinct yellow coloration, facilitating real-time detection in assay development and enzyme activity profiling. The compound exhibits excellent stability under standard conditions and is well-suited for high-throughput screening workflows.
Synthesis
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Route1
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100-02-7 -
In-stock
2616-64-0 - ~%
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In-stock
10344-94-2
References
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Chemical and Pharmaceutical Bulletin, , vol. 58, # 3 p. 423 - 425
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Route2
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100-02-7
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In-stock
63700-19-6 - ~%
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In-stock
10344-94-2
References
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Steroids, , vol. 76, # 13 p. 1465 - 1473
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Route3
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100-02-7
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1245697-26-0
- ~%
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In-stock
10344-94-2
References
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Pharmaceutical Research, , vol. 29, # 6 p. 1544 - 1561
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Quality Control
Computational Chemistry Data
- TPSA 159.59
- LogP -1.1342
- H_Acceptors 8
- H_Donors 4
- Rotatable_Bonds 4
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