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CS-W001157 4
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Propargyl-PEG5-OH

  • CAS No. 1036204-60-0

  • Cat. No. CS-0105254
  • Molecule weight276.33
  • Purity≥95%
  • MDL No.MFCD27635181

*For research and further manufacturing use only, not for direct human use.

Propargyl-PEG5-OH|CS-0105254

Structure of 1036204-60-0

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General Information

  • CAS No. 1036204-60-0
  • Cat. No. CS-0105254
  • Purity ≥95%
  • MDL No. MFCD27635181
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₄O₆
  • Molecular Weight 276.33
  • Synonym(s) None
  • SMILES OCCOCCOCCOCCOCCOCC#C

Description

Propargyl-PEG5-OH is a water-soluble, bench-stable linker featuring a terminal alkyne for bioconjugation and a hydroxyl-terminated PEG chain. This molecule integrates seamlessly into click chemistry workflows, enabling efficient coupling with azide-functionalized biomolecules under mild conditions. The five-ethylene glycol units provide enhanced solubility and reduced non-specific binding in aqueous environments.

Application

Propargyl-PEG5-OH serves as a versatile bifunctional linker for conjugation and polymer synthesis, combining the reactivity of a terminal alkyne with the solubility and stability of a PEG5 spacer. It facilitates efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) while maintaining excellent solubility in aqueous and organic media, enabling straightforward purification and broad functional group tolerance in bioconjugation and materials chemistry applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P210-P261-P264-P271-P280-P302+P352-P304+P340-P370+P378-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   66.38
  • LogP   -0.3051
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   15

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