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CS-W001157 4
Total: USD 88.00

5-Bromo-4-methoxy-2-nitrobenzaldehyde

  • CAS No. 1036757-01-3

  • Cat. No. CS-0188791
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Bromo-4-methoxy-2-nitrobenzaldehyde|CS-0188791

Structure of 1036757-01-3

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General Information

  • CAS No. 1036757-01-3
  • Cat. No. CS-0188791
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆BrNO₄
  • Molecular Weight 260.04
  • Synonym(s) None
  • SMILES O=CC1=CC(Br)=C(OC)C=C1[N+]([O-])=O

Description

5-Bromo-4-methoxy-2-nitrobenzaldehyde features a trifunctional aromatic core with bromine, methoxy, and nitro groups positioned for orthogonal reactivity. The aldehyde moiety enables direct coupling in cross-coupling or condensation reactions. This electron-deficient scaffold offers enhanced stability under standard conditions while maintaining high reactivity in transition-metal-catalyzed transformations.

Application

5-Bromo-4-methoxy-2-nitrobenzaldehyde serves as a versatile building block in the synthesis of functionalized heterocycles and pharmaceutical intermediates. Its ortho-nitro and aldehyde groups enable sequential transformations, while the bromo and methoxy substituents offer sites for palladium-catalyzed coupling and selective derivatization. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic workflows in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P501

Quality Control

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Computational Chemistry Data

  • TPSA   69.44
  • LogP   2.1784
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   3

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