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Structure of 103877-76-5
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This difluorinated benzoic acid features a methyl group at the 4-position and fluorine atoms at the 3- and 5-positions, creating a highly electron-deficient aromatic core. The combination enhances metabolic stability and improves membrane permeability, making it valuable in medicinal chemistry for constructing bioactive scaffolds.
3,5-Difluoro-4-methylbenzoic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and drug candidates. Its ortho-fluorinated aryl core enhances metabolic stability and modulates electronic properties, while the carboxylic acid group facilitates direct coupling reactions or derivatization. The methyl substituent provides a site for further functionalization. This compound exhibits excellent bench stability and compatibility with standard synthetic protocols, making it ideal for scalable synthesis and structure–activity studies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: