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CS-W001157 4
Total: USD 88.00

2-(1-(4-Methoxyphenyl)vinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

  • CAS No. 1038849-76-1

  • Cat. No. CS-0437053
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(1-(4-Methoxyphenyl)vinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0437053

Structure of 1038849-76-1

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General Information

  • CAS No. 1038849-76-1
  • Cat. No. CS-0437053
  • Purity ≥98%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₁BO₃
  • Molecular Weight 260.14
  • Synonym(s) None
  • SMILES CC1(C)C(C)(C)OB(C(C2=CC=C(OC)C=C2)=C)O1

Description

This boronate ester features a para-methoxyphenyl vinyl linkage, delivering enhanced stability and compatibility in cross-coupling reactions. The tetramethyl-substituted dioxaborolane ring ensures excellent shelf life and moisture tolerance, enabling reliable use under standard conditions.

Application

2-(1-(4-Methoxyphenyl)vinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. Its vinylboronate functionality enables efficient coupling with aryl and heteroaryl halides under mild conditions, facilitating the construction of conjugated biaryl systems. The tetramethyl-substituted dioxaborolane ring enhances stability and simplifies purification, while the para-methoxy group provides predictable electronic modulation. Ideal for synthetic routes requiring reliable, functional group-tolerant coupling partners.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   27.69
  • LogP   3.3398
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

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