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Structure of 103979-08-4
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2-Bromo-3-fluoro-6-nitrophenol features a trifunctional aromatic core with bromine, fluorine, and nitro groups positioned for orthogonal reactivity. This electron-deficient phenol enables selective coupling in cross-coupling and electrophilic substitution reactions. The molecule exhibits enhanced stability under standard conditions, facilitating handling and integration into complex synthetic sequences.
2-Bromo-3-fluoro-6-nitrophenol serves as a versatile building block for the synthesis of functionalized aromatic scaffolds, enabling direct coupling in Pd-catalyzed cross-coupling reactions. The ortho-bromo and nitro groups provide complementary reactivity for sequential transformations, while the fluorine substituent enhances regioselectivity in electrophilic substitution. Its bench-stable solid form facilitates handling and purification, making it suitable for iterative synthetic sequences in medicinal chemistry and materials development.
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GHS Pictogram :
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GHS No : GHS05,GHS07,GHS09
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Signal Word : Danger
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H317-H318-H410
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Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P391-P501
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Lot numbers can be found on the outside label of a product: