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Structure of 1040377-18-1
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This boronate-functionalized pyrazole integrates readily into Suzuki-Miyaura coupling reactions under standard conditions. The tetramethyl-1,3,2-dioxaborolan-2-yl moiety ensures excellent stability and reactivity, while the tertiary alcohol group provides solubility and steric protection. Designed for efficient C–C bond formation in complex molecule synthesis.
2-Methyl-2-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propan-1-ol serves as a stable, bench-ready boronate building block for palladium-catalyzed cross-coupling reactions. Its tetramethylboronate group enables efficient Suzuki-Miyaura coupling under mild conditions, while the sterically hindered tertiary alcohol imparts enhanced stability and ease of purification. The pyrazole core provides a versatile heterocyclic scaffold for medicinal chemistry applications, with broad functional group tolerance facilitating downstream derivatization in complex molecule synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: