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Structure of 10406-06-1
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5-Bromo-1H-indole-3-carboxylic acid features a bromine substituent at the 5-position of the indole core, enhancing electrophilic reactivity and enabling downstream functionalization. The carboxylic acid group provides a handle for amide coupling or esterification under standard conditions. This bench-stable compound serves as a key intermediate in medicinal chemistry and materials synthesis, particularly for heterocyclic systems requiring halogenated aromatic scaffolds.
5-Bromo-1H-indole-3-carboxylic acid serves as a versatile building block for the synthesis of indole-based pharmaceuticals and functional materials. The bromo group enables palladium-catalyzed cross-coupling reactions, while the carboxylic acid facilitates amide formation, esterification, or direct derivatization. Its stability under standard bench conditions and compatibility with common protecting group strategies make it well-suited for iterative synthetic sequences in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: