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Structure of 104103-06-2
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4-Methyl-7-nitro-1H-indazole is a bench-stable, electron-deficient heterocycle featuring a nitro group at the 7-position and a methyl substituent at the 4-position. This combination enhances regioselectivity in cross-coupling reactions and improves solubility in polar organic solvents. The compound serves as a key scaffold in medicinal chemistry for developing kinase inhibitors and bioactive small molecules.
4-Methyl-7-nitro-1H-indazole serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the indazole core due to its complementary electron-withdrawing nitro group and methyl substituent. The nitro group facilitates subsequent reduction to amine intermediates or participates in coupling reactions, while the methyl group provides a handle for selective oxidation or C–H activation. Bench-stable and compatible with standard purification methods, it functions effectively in multistep syntheses of bioactive heterocycles and API candidates.
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GHS Pictogram :
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GHS No : GHS06,GHS08
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H319-H351-H360
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Precautionary Statements : P264-P270-P280-P330-P405-P501
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Lot numbers can be found on the outside label of a product: