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Structure of 1044145-59-6
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This bench-stable, moisture-tolerant pyrimidine derivative features a chlorinated heterocycle paired with a methylthio group and a terminal hydroxymethyl functionality. The para-chloro substitution enhances electrophilic reactivity, while the methanol handle enables straightforward derivatization in late-stage functionalization.
(4-Chloro-2-(methylthio)pyrimidin-5-yl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrimidine-based scaffolds. The pendant alcohol facilitates derivatization via esterification, etherification, or coupling reactions, while the chloro and methylthio groups offer orthogonal reactivity for nucleophilic substitution and transition-metal-catalyzed cross-coupling. Its bench-stable nature and compatibility with standard synthetic protocols make it well-suited for modular synthesis of bioactive compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: