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Structure of 1044507-52-9
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3-(3-Bromophenyl)oxetane is a bench-stable, moisture-tolerant heterocyclic building block featuring a brominated aromatic ring fused to a strained oxetane core. This combination enables direct functionalization in late-stage diversification, particularly in cross-coupling and C–H activation processes. The electron-deficient bromine facilitates palladium-mediated transformations while the oxetane ring enhances solubility and metabolic stability in bioactive molecule design.
3-(3-Bromophenyl)oxetane serves as a versatile building block for the synthesis of biologically active molecules, enabling efficient C–H functionalization and transition-metal-catalyzed coupling reactions. Its oxetane ring imparts enhanced metabolic stability and favorable physicochemical properties, while the ortho-bromo substituent facilitates palladium-catalyzed cross-coupling with broad functional group tolerance. The compound exhibits excellent bench stability and ease of purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: