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Structure of 1044764-69-3
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This boronate-containing scaffold features a protected amine and electron-deficient aromatic core, enabling direct incorporation into peptide macrocycles. The tert-butyl ester group provides enhanced stability during purification and storage, while the isoindoline framework offers rigidity for conformational control in bioactive molecule design.
2-(tert-Butoxycarbonyl)isoindoline-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the efficient synthesis of isoindoline-based scaffolds prevalent in bioactive molecules. The Boc group provides excellent stability and orthogonal deprotection compatibility, while the carboxylic acid functionality facilitates direct coupling reactions. Its robustness under standard peptide and heterocyclic coupling conditions makes it ideal for modular library construction and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: