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Structure of 1044768-44-6
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4-Chloro-6-fluoro-2-methylquinazoline is a heterocyclic scaffold featuring complementary electron-withdrawing halogens and a methyl group at the 2-position, enhancing its utility in medicinal chemistry. This bench-stable compound integrates readily into kinase inhibitor architectures and serves as a key intermediate for targeted therapeutics.
4-Chloro-6-fluoro-2-methylquinazoline serves as a versatile building block in medicinal chemistry, enabling efficient access to kinase inhibitor scaffolds. Its electron-deficient quinazoline core facilitates nucleophilic substitution and transition-metal-catalyzed coupling reactions. The strategically positioned chloro and fluoro groups offer orthogonal reactivity for sequential functionalization, while the methyl group enhances metabolic stability. Bench-stable and compatible with standard purification methods, it functions reliably in multi-step syntheses of bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: