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Structure of 1045795-70-7
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Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)benzoate features a boronate ester group flanked by electron-withdrawing trifluoromethyl and ester functionalities, enabling efficient Suzuki-Miyaura coupling under standard conditions. This bench-stable reagent integrates readily into complex molecular architectures, delivering high functional group tolerance and predictable reaction outcomes in medicinal chemistry and materials synthesis workflows.
Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)benzoate serves as a robust boronate building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylborolane moiety provides excellent stability and shelf life, while the trifluoromethyl and ester functionalities offer orthogonal reactivity and compatibility with diverse synthetic transformations. This reagent enables efficient construction of biaryl and heterocyclic scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: