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CS-W001157 4
Total: USD 88.00

5,6,7,8-Tetrahydro-quinoline

  • CAS No. 10500-57-9

  • Cat. No. CS-0173570
  • Purity≥98%
  • MDL No.MFCD00006734
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5,6,7,8-Tetrahydro-quinoline|CS-0173570

Structure of 10500-57-9

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Description

5,6,7,8-Tetrahydroquinoline serves as a key heterocyclic scaffold in medicinal chemistry, offering enhanced metabolic stability and favorable pharmacokinetic properties. This saturated quinoline derivative integrates readily into bioactive molecules, where its electron-rich aromatic system supports hydrogen bonding and π-stacking interactions. The compound exhibits robust bench stability and compatibility with standard synthetic protocols.

Application

5,6,7,8-Tetrahydroquinoline serves as a versatile scaffold in medicinal chemistry, enabling rapid access to bioactive heterocycles through standard functionalization at the nitrogen and aromatic positions. Its stability under physiological conditions and compatibility with common coupling reactions make it a practical building block for drug discovery programs requiring modifiable, lipophilic frameworks.

General Information

  • CAS No. 10500-57-9
  • Cat. No. CS-0173570
  • Purity ≥98%
  • MDL No. MFCD00006734
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁N
  • Molecular Weight 133.19
  • Synonym(s) 5,6,7,8-Tetrahydroquinoline; 2,3-Cyclohexenopyridine
  • SMILES C12=C(N=CC=C2)CCCC1

Computational Chemistry Data

  • TPSA   12.89
  • LogP   1.9604
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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