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Structure of 1053659-39-4
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3-Bromo-6-chloropyridine-2-carbonitrile features a trifunctional pyridine core bearing bromo, chloro, and nitrile groups at strategic positions, enabling direct incorporation into cross-coupling and cyclization cascades. The electron-deficient aromatic ring facilitates nucleophilic substitution, while the carbonitrile group serves as a handle for derivatization. This compound exhibits bench-stable behavior under standard conditions and integrates efficiently into complex heterocyclic architectures.
3-Bromo-6-chloropyridine-2-carbonitrile serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogenation pattern. The bromo group facilitates Suzuki, Stille, or Negishi coupling, while the chloro and nitrile functionalities offer additional sites for selective functionalization. Its bench-stable nature and compatibility with standard reaction conditions make it ideal for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H318-H335
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: