Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Hydroxy-3,5-di(propan-2-yl)benzaldehyde

  • CAS No. 10537-86-7

  • Cat. No. CS-0061022
  • Molecule weight206.28
  • Purity≥97%
  • MDL No.MFCD00812875

*For research and further manufacturing use only, not for direct human use.

4-Hydroxy-3,5-di(propan-2-yl)benzaldehyde|CS-0061022

Structure of 10537-86-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 10537-86-7
  • Cat. No. CS-0061022
  • Purity ≥97%
  • MDL No. MFCD00812875
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₈O₂
  • Molecular Weight 206.28
  • Synonym(s) 4-Hydroxy-3,5-bis(isopropyl)benzaldehyde
  • SMILES CC(C)C1=C(C(=CC(=C1)C=O)C(C)C)O

Description

This sterically shielded aldehyde features a hydroxyl group flanked by two isopropyl substituents, delivering enhanced stability and solubility in organic media. The para-hydroxy and ortho-isopropyl arrangement enables selective functionalization in complex synthesis, particularly useful for phenolic scaffold construction under mild conditions.

Application

4-Hydroxy-3,5-di(propan-2-yl)benzaldehyde serves as a versatile phenolic aldehyde scaffold for the synthesis of bioactive heterocycles and functionalized aromatic systems. Its ortho-hydroxyl and para-aldehyde groups enable sequential derivatization, while the bulky tert-butyl substituents confer enhanced steric protection and bench stability. The compound facilitates efficient coupling reactions and acts as a key building block in the construction of antioxidant motifs and pharmaceutical intermediates.

Synthesis

  • Route1
    • null|null
      1336-21-6
    • Propofol emulsion|CS-1692821
      2078-54-8
    • ~%
    • In-stock
      4-Hydroxy-3,5-di(propan-2-yl)benzaldehyde|CS-0061022
      10537-86-7

    References

    • US2003/119790 A1, ;
  • Route2
    • Propofol emulsion|CS-1692821
      2078-54-8
    • null|null
      4885-02-3
    • ~77%
    • In-stock
      4-Hydroxy-3,5-di(propan-2-yl)benzaldehyde|CS-0061022
      10537-86-7

    References

    • Ieda, Naoya; Nakagawa, Hidehiko; Horinouchi, Taeko; Peng, Tao; Yang, Dan; Tsumoto, Hiroki; Suzuki, Takayoshi; Fukuhara, Kiyoshi; Miyata, Naoki Chemical Communications, 2011 , vol. 47, # 22 p. 6449 - 6451
  • Route3
    • Propofol emulsion|CS-1692821
      2078-54-8
    • null|null
      100-97-0
    • ~97%
    • In-stock
      4-Hydroxy-3,5-di(propan-2-yl)benzaldehyde|CS-0061022
      10537-86-7

    References

    • Geurink, Paul P.; Florea, Bogdan I.; Li, Nan; Witte, Martin D.; Verasdonck, Joeri; Kuo, Chi-Lin; Van Der Marel, Gijs A.; Overkleeft, Herman S. Angewandte Chemie - International Edition, 2010 , vol. 49, # 38 p. 6802 - 6805

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   37.3
  • LogP   3.4515
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 10537-86-7 sigma10537-86-7 manufacturer10537-86-7 price10537-86-7 structure10537-86-7 SDSbuy 10537-86-710537-86-7 supplier10537-86-7 uses10537-86-7 molecular weightprice of 10537-86-710537-86-7 chemical name formula of 10537-86-7
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label